MAP3K5 Polyclonal Antibody-抗体-抗体-生物在线

MAP3K5 Polyclonal Antibody

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产品名称： MAP3K5 Polyclonal Antibody

英文名称： MAP3K5 Polyclonal Antibody

产品编号： K001658P

产品价格： null

产品产地：北京市通州区马驹桥联

品牌商标： solarbio

更新时间： 2025-01-02T09:53:49

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北京索莱宝科技有限公司

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产品详情

Anti-MAP3K5 Polyclonal Antibody
品牌：Solarbio | 货号：K001658P




英文名称 Anti-MAP3K5 Polyclonal Antibody
宿主 Rabbit
别名 ASK1;MAPKKK5;MEKK5
应用 WB
稀释比例 WB 1:500-1:2000.
交叉反应 Human Mouse
蛋白分子量 155kDa
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human MAP3K5
Subcellular 

Locations Cytoplasm Endoplasmic reticulum
Swiss Prot Q99683
克隆类型 Polyclonal Antibody
背景资料 Mitogen-activated protein kinase (MAPK) signaling 
cascades include MAPK or extracellular signal-regulated 
kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase 
kinase (MAPKKK or MEKK). MAPKK kinase/MEKK 
phosphorylates and activates its downstream protein 
kinase, MAPK kinase/MEK, which in turn activates MAPK. 
The kinases of these signaling cascades are highly 
conserved, and homologs exist in yeast, Drosophila, and 
mammalian cells. MAPKKK5 contains 1,374 amino acids with 
all 11 kinase subdomains. Northern blot analysis shows that 
MAPKKK5 transcript is abundantly expressed in human 
heart and pancreas. The MAPKKK5 protein phosphorylates 
and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and 
activates c-Jun N-terminal kinase (JNK)/stress-activated 
protein kinase (SAPK) during transient expression in COS 
and 293 cells; MAPKKK5 does not activate MAPK/ERK.

英文名称	Anti-MAP3K5 Polyclonal Antibody
宿主	Rabbit
别名	ASK1;MAPKKK5;MEKK5
应用	WB
稀释比例	WB 1:500-1:2000.
交叉反应	Human Mouse
蛋白分子量	155kDa
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human MAP3K5
Subcellular Locations	Cytoplasm Endoplasmic reticulum
Swiss Prot	Q99683
克隆类型	Polyclonal Antibody
背景资料	Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.